The discovery of functionally diverse membrane pyrophosphatase subfamilies
نویسندگان
چکیده
منابع مشابه
The functionally diverse roles of tribbles.
Tribbles are members of the pseudokinase family of proteins, with no associated kinase activity detectable to date. As tribbles appear not to function as kinases, there has been debate surrounding their functional classification. Tribbles have been proposed to function as adaptor molecules facilitating degradation of their target proteins. Tribbles have also been proposed to mediate signalling ...
متن کاملChemical pyrophosphorylation of functionally diverse peptides.
A highly selective and convenient method for the synthesis of pyrophosphopeptides in solution is reported. The remarkable compatibility with functional groups (alcohol, thiol, amine, carboxylic acid) in the peptide substrates suggests that the intrinsic nucleophilicity of the phosphoserine residue is much higher than previously appreciated. Because the methodology operates in polar solvents, in...
متن کاملNematode Hsp90: highly conserved but functionally diverse.
Nematodes are amongst the most successful and abundant organisms on the planet with approximately 30 000 species described, although the actual number of species is estimated to be one million or more. Despite sharing a relatively simple and invariant body plan, there is considerable diversity within the phylum. Nematodes have evolved to colonize most ecological niches, and can be free-living o...
متن کاملResolving the Conflict-creativity Tension in Functionally Diverse Innovation Teams
More and more organizations structure their innovation projects around functionally diverse teams. Why are some diverse teams more innovative than others? In my dissertation research, I investigate how cognitive diversity, conflict, and creativity affect the success of functionally-diverse innovation teams. Some research points to the importance of cognitive diversity for stimulating group crea...
متن کاملA note on reliability estimation of functionally diverse systems
It has been argued that functional diversity might be a plausible means of claiming independence of failures between two versions of a system. We present a model of functional diversity, in the spirit of earlier models of diversity such as those of Eckhardt and Lee, and Hughes. In terms of the model, we show that claims for independence between functionally diverse systems seem rather unrealist...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Bioenergetics
سال: 2014
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2014.05.268